ChromSwordAuto Chromeleon Connect and Fusion QbD software significantly accelerates this step by rapidly analyzing separation data and automatically optimizing the HPLC method. This is the most time-consuming stage of method development and requires a great deal of user experience and knowledge.
Operators must run many samples and repeatedly make decisions based on results. Method optimization, involving iterative testing of various separation conditions of the HPLC method, is performed to achieve the best possible resolution, speed, etc.This process can be automated and streamlined using Viper fingertight fittings and solvent extension kits, and software packages such as ChromSwordAuto Chromeleon Connect and Fusion QbD.
Traditionally, method scouting requires a significant amount of effort for manual column and mobile phase switching as well as instrument method creation.